Peak Biologics is an Authorized Distributor of...

CanisCell Products
EquusCell Products

AniCell Biotech offers affordable, regenerative, wound-care products derived from amnion and amniotic fluid/tissue collected non-invasively at birth of horses and dogs. A complete product line of cellular and acellular bioscaffolds designed for management of fractured bones, damaged ligaments, torn tendons, joint and cartilage damage, eye injuries and superficial wounds (including burns and puncture wounds. Treatments are available singular dose, right off-the-shelf, with in-the-field application the same day as diagnosis.  All Anicell Biotech products have a consistent profile and high efficacy rates.

don't repair – regenerate

PEAK BIOLOGICS is committed to the safe, efficacious treatment of our clients. We believe in REGENERATION of normal tissue, not healing via scar tissue formation. Amnion/Amniotic Fluid derived biologic therapy follows the 2 most important treatment paradigms:

1st – Before all else, DO NO HARM

2nd – Mechanism of Action meshes perfectly with the pathophysiology of the disease to be treated.

Advantages of Anicell Amnion Treatments: 

  • Safer: A non-invasive procedure that does not require "creating a wound to cure a wound". No painful harvesting of bone marrow or fat. No sedation or anesthetics required.
  • Better: Amniotic Material is regenerative fetal material safely collected during parturition. It includes the basic building blocks of the Extra Cellular Matrix (ECM) such as collagen, thus creating a structure to promote growth and enhanced tissue quality.
  • Faster: Amnion is immune privileged. It lacks the MHC type ll expression (blood antigens) that would normally elicit an inflammatory immune response. This means the body will not recognize it as a foreign tissue and it can be used the same day as diagnosis.
  • Lower Cost: No collection kit or shipping required as there is for fat or bone marrow samples. No culturing or lab work needed.
  • Convenient: AniCell Biotech products can be used immediately in the field during the acute inflammatory signaling phase of wounds to promote healthy tissue by supplying all the necessary scaffolding material for fibroblasts to repair the ECM properly.

Properties of AniCell BioTech’s amniotic membrane and amnion-derived products.

Amniotic materials have several properties that confer suitability as a wound covering or “biological bandage”. These include:

  1. Biocompatiblity– Low or nonimmunogenicity of the tissue impedes rejection by the animal host.

Reference: Hori J, et al. (2006) Immunological characteristics of amniotic epithelium. Cornea 25: S53-S58

  1. Durability– The complexity and unique arrangement of specialized structural proteins (collagen, laminin, elastin, proteoglycans, glycoproteins, glycosaminoglycans, etc.) provide substantial mechanical integrity and viscoelastic properties that are important for forming a barrier to protect and separate wounds from the outside environment.

Reference: Niknejad H, et al. (2008) Properties of the amniotic membrane for potential use in tissue engineering. Eur Cell Mater 15: 88-99

  1. Hydratabililty– The high concentration of carbohydrate side-groups in the extracellular matrix molecules that comprise the amniotic membrane allow for generous hydration of the biomaterial, which can be beneficial for decreasing wound dehydration and requiring fewer dressing changes.

Reference: Loeffelbein DJ, et al. (2014) Evaluation of Human Amniotic Membrane as a Wound Dressing for Split-Thickness Skin-Graft Donor Sites. BioMed Res Int 2014: Article ID 572183

  1. Resorbability– Since the natural amniotic membrane biomaterial is resorbable, it does not have to be physically removed from the wound after application which could perturb the wound bed and generate greater trauma.

Reference: Branski LK, et al. (2008) Amnion in the treatment of pediatric partial-thickness facial burns. Burns 343: 393-399

  1. Self-adherence– As a naturally adhesive substrate and biomaterial, the amnion is adherent to wounds and permissive to cell adhesion and ingrowth, acting as a scaffold when the animal’s body is building new tissue.

Reference: Koizumi N, et al. (2007) Comparison of intact and denuded amniotic membrane as a substrate for cell-suspension culture of human limbal epithelial cells. Graefes Arch Clin Exp Ophthalmol 24: 123

  1. Semipermeability- Gas exchange through the membrane material provides a healthy environment for allowing the animal’s own healing mechanisms to progress.

Reference: Hopf HW and Rollins MD. (2006) Wounds: An overview of the role of oxygen. Antioxid Redox Signal 9: 1183-1192