Peak Biologics is an Authorized Distributor of...

CanisCell Products
EquusCell Products

AniCell Biotech offers affordable, regenerative, wound-care products derived from amnion and amniotic fluid/tissue collected non-invasively at birth of horses and dogs. A complete product line of cellular and acellular bioscaffolds designed for management of fractured bones, damaged ligaments, torn tendons, joint and cartilage damage, eye injuries and superficial wounds (including burns and puncture wounds. Treatments are available singular dose, right off-the-shelf, with in-the-field application the same day as diagnosis.  All Anicell Biotech products have a consistent profile and high efficacy rates.

don't repair – regenerate

PEAK BIOLOGICS is committed to the safe, efficacious treatment of our clients. We believe in REGENERATION of normal tissue, not healing via scar tissue formation. Amnion/Amniotic Fluid derived biologic therapy follows the 2 most important treatment paradigms:

1st – Before all else, DO NO HARM

2nd – Mechanism of Action meshes perfectly with the pathophysiology of the disease to be treated.

Advantages of Anicell Amnion Treatments: 

  • Safer: A non-invasive procedure that does not require "creating a wound to cure a wound". No painful harvesting of bone marrow or fat. No sedation or anesthetics required.
  • Better: Amniotic Material is regenerative fetal material safely collected during parturition. It includes the basic building blocks of the Extra Cellular Matrix (ECM) such as collagen, thus creating a structure to promote growth and enhanced tissue quality.
  • Faster: Amnion is immune privileged. It lacks the MHC type ll expression (blood antigens) that would normally elicit an inflammatory immune response. This means the body will not recognize it as a foreign tissue and it can be used the same day as diagnosis.
  • Lower Cost: No collection kit or shipping required as there is for fat or bone marrow samples. No culturing or lab work needed.
  • Convenient: AniCell Biotech products can be used immediately in the field during the acute inflammatory signaling phase of wounds to promote healthy tissue by supplying all the necessary scaffolding material for fibroblasts to repair the ECM properly.

Impact of Amnion on the Tissue Healing Cascade:   Augmenting Mother Nature's powerful process!

1.) Hemostasis

  • Collagen fibers of the amniotic basement membrane have hemostatic properties that prevent hematoma formation in clean surgical wounds.

2.) Inflammation

  • Secretes anti-inflammatory proteins such as Activin A, lL-1 receptor antagonist (lL-1ra), lL6 and lL-10
  • Suppresses T lymphocyte proliferation.
  • Attracts and activates macrophages.
  • Entraps inflammatory cells by hyaluronic acid acting as a ligand for CD44.
  • Suppresses pro-inflammatory cytokines IL-1a, lL1β, and TNFa.

3.) Repair

  • Extensive expression of cytokines found in amniotic membrane.
  • Spawns the attraction of fibroblasts.
  • Promotes cellular signaling through cytokines.
  • Anti-fibrotic by suppressing fibrosis through down-regulating TGF-β and it's receptor expression
  • Increases Anti-fibrotic granulation providing the specific collagen needed for repair.

4.) Remodeling

  • Produces neovascularization in a controlled manner. Produces angiogenic factors such as VEGF and bFGF for neovasvularization and suppresses anti-angiogenic factors (endostatin, TSP-1, and TimPs).